The PARADIM Materials Innovation Platform has launched a revolutionary, streaming-data-based approach to the design and creation of new interface materials – new materials with the unprecedented properties needed to realize exciting technologies like quantum computing. PARADIM is a state-of-the-art scientific facility at Cornell, Johns Hopkins, and Clark Atlanta Universities that produces a firehose of complex and highly varied data. To build our data layer we’ve implemented Apache Kafka with newly developed, end-to-end encryption to connect our instruments, users, and world-class experts. Data reduction, analysis and management connect seamlessly to real-time ML tools in an integrated materials design workflow. At PARADIM, this flexible, scalable, and fault-tolerant data streaming is creating a new paradigm for collaborative science in the age of materials Big Data.